TRULICITY (Dulaglutide Injection) For Diabetes

TRULICITY (Dulaglutide Injection) For Diabetes

Once-Weekly GLP-1 Therapy for Type 2 Diabetes Management

Trulicity is a long-acting prescription medication containing Dulaglutide. It is indicated for the treatment of adults with insufficiently controlled Type 2 diabetes as an adjunct to diet and exercise. It mimics the natural hormone GLP-1 to help the body lower blood sugar levels when they are too high and supports heart health in patients with established cardiovascular risk factors.

Key Therapeutic Actions

• Glycaemic Control: Improves blood sugar management by stimulating insulin secretion only when glucose levels are elevated.

• Glucagon Regulation: Reduces the amount of sugar the liver produces.

• Cardiovascular Risk Reduction: Indicated to reduce the risk of major adverse cardiovascular events in adults with Type 2 diabetes and established cardiovascular disease or multiple risk factors.

How to Use (Once-Weekly Administration)

• Schedule: Inject Trulicity once a week, on the same day each week.

• Technique: The pre-filled pen is designed for subcutaneous injection into the abdomen, thigh, or upper arm. Rotate the injection site each week.

• Convenience: Can be administered at any time of day, regardless of meals.

• Missed Dose: If you miss a dose, take it within 3 days (72 hours). If more than 3 days have passed, skip the dose and wait for your next regularly scheduled injection.

  Critical Safety Information

• Thyroid Cancer Warning: In animal studies, dulaglutide caused thyroid tumours. It is unknown if it causes these in humans. Do not use if you or your family have a history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

• Pancreatitis: Seek immediate medical help if you experience severe, persistent stomach pain that radiates to your back, as this may be a sign of pancreatitis.

• Kidney Function: Dehydration caused by nausea or diarrhoea can lead to kidney problems. Ensure you maintain adequate fluid intake.

• Severe Gastrointestinal Disease: Trulicity is not recommended for patients with severe stomach problems, such as gastroparesis.

Possible Side Effects

• Very Common: Nausea, vomiting, diarrhoea, and abdominal pain. These effects are usually mild to moderate and most frequent during the start of treatment.

• Hypoglycaemia: While Trulicity alone rarely causes low blood sugar, the risk increases if used with insulin or sulphonylureas.

• Heart Rate: Some patients may experience a slight increase in resting heart rate.

Composition & Storage

• Active Ingredient: Dulaglutide (0.75mg or 1.5mg).

• Cold Chain Storage: Store in a refrigerator (2°C to 8°C). Do not freeze.

• Room Temperature: If necessary, a single pen can be kept at room temperature (below 30°C) for up to 14 days, after which it must be discarded.

• Light Protection: Keep the pen in the original carton to protect it from light.