Premarin is a combination oestrogen treatment that helps to relieve menopause symptoms like hot flushes, night-sweats, and dryness of the genitals. Premarin treatment can help prevent bone loss that can occur after menopause. This can lead to osteoporosis. Premarin is available in tablet form, and should be taken every day. Premarin is sometimes prescribed with progestogen for women who have not had an hysterectomy.