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Cytisine

Cytisine tablets (1.5mg) can help reduce nicotine cravings during stop smoking attempts. Available to buy online from Online Pharmacy 4U.

About cytisine

  • Cytisine 1.5mg is a prescription-only tablet used reduce to nicotine cravings during quit smoking attempts.
  • 100 tablets is a standard course of treatment, taken over 25 days.
  • Cytisine is safe and effective, increasing stop smoking success by approximately 75% compared with placebo.
  • Evidence suggests that 25 days of cytisine treatment is as effective as nicotine replacement therapy but cytisine also weans you off nicotine.
  • Cytisine has no known serious side effects.
  • Read the patient leaflet for a full list of side effects, cautions, and interactions with other drugs.

How cytisine works

Tobacco contains nicotine. When you smoke, nicotine is absorbed through your lungs into your blood. When nicotine reaches your brain it stimulates the release of neurotransmitters including dopamine, which acts to cause feelings of pleasure, often leading to nicotine addiction.

When you stop smoking you no longer stimulate the production of dopamine and you may experience a variety of symptoms such as craving a cigarette, feeling restless, a change in mood, or trouble sleeping. For most people who stop smoking, these withdrawal symptoms are worse in the first few days to a couple of weeks, then they reduce in strength and frequency.

Cytisine works by attaching to some of the same receptors in the brain as nicotine, reducing the pleasurable feelings experienced when using nicotine-containing products. Cytisine increases the likelihood you will stop smoking by approximately 75% compared with placebo, but also allows a gradual reduction in nicotine dependence. Compared with nicotine replacement therapy, where the body remains addicted to nicotine, cytisine has the additional benefit of weaning you off nicotine.

How to take cytisine

  • Each tablet contains 1.5mg of cytisine.
  • One pack of cytisine contains 100 tablets - a complete course of treatment (25 days).
  • Cytisine should be taken with water according to the schedule below.
  • Each day, following your 1st dose of cytisine, we suggest you set a reminder / alarm for the next dose.
  • Note: your quit smoking date should be no later than day 5. Continued smoking may worsen any treatment reaction.
  • If you miss a dose of cytisine you should not take a double dose to make up for it. You should just take the next dose as indicated.
Cytisine 25-day schedule of treatment to reduce nicotine cravings
Days of treatment Recommended dosing Maximum daily dose
From the 4th to the 12th day 1 tablet every 2.5 hours 5 tablets
From the 13th to the 16th day 1 tablet every 3 hours 4 tablets
From the 17th to the 20th day 1 tablet every 5 hours 3 tablets
From the 21st to the 25th day 1-2 tablets a day 2 tablets

An alternative version of the treatment schedule which you may find easier to follow (from the National Centre for Smoking Cessation and Training).

Cytisine summary and dosing guide

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